Structure, regulation and function of ghrelin
نویسندگان
چکیده
منابع مشابه
Ghrelin: structure and function.
Small synthetic molecules called growth hormone secretagogues (GHSs) stimulate the release of growth hormone (GH) from the pituitary. They act through the GHS-R, a G protein-coupled receptor whose ligand has only been discovered recently. Using a reverse pharmacology paradigm with a stable cell line expressing GHS-R, we purified an endogenous ligand for GHS-R from rat stomach and named it "ghre...
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Epithelial and/or endothelial barriers play a critical role in animal, including human, life forms. The tight junction (TJ) is an essential component of these barriers. Occludin is a major component of the TJ. The structure of occludin, including its gene splice variants and protein essential components have been elucidated. Phosphorylation/dephosphorylation plays a major role in regulation of ...
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one of the main members of the large aggregating proteoglycans (pgs) family is versican which is able to bind to hyaluronate. versican is a chondroitin sulfate proteoglycan and is a key ingredient of the extracellular matrix. due to its widespread expression in the body, versican is involved in cell adhesion, proliferation and migration. induced expression of versican is often observed in tiss...
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ژورنال
عنوان ژورنال: Journal of Biochemistry
سال: 2011
ISSN: 0021-924X
DOI: 10.1093/jb/mvr134